Antifungal drugs in gynecology for women, suppositories. Antifungal suppositories for women: list of effective drugs, reviews. Side effects of suppositories for candidiasis

Inflammatory diseases of the reproductive system in women always carry the risk of developing infertility and other more serious complications. One of these disorders includes candidiasis, or thrush.

This infection is associated with the unnatural proliferation of microscopic fungi and their spread along the vaginal mucosa. This causes discomfort during movements and sexual intercourse, itching, burning and the appearance of white “curdled” discharge. The cause of this pathological disorder is a decrease in immunity, dysbiosis, taking certain groups of medications, previous diseases, etc.

To alleviate such unpleasant manifestations and symptoms, effective tablets, antifungal suppositories and other medications have been created for women to treat thrush, incl. and inexpensive. The most common means used for this disorder are vaginal suppositories. This article will discuss what medicinal suppositories exist to eliminate this pathology.

The most popular and effective vaginal suppositories

These include relatively inexpensive drugs that are popular among women and have wide range use as prescribed by doctors. In complex treatment, tablets and other medicines for the treatment of the lesion that caused the development of candidiasis.

Conventionally, all suppositories can be divided into 2 groups, differing in the course of use and the speed of relief and elimination of symptoms in women. Each of the presented products has its own inexpensive analogues and other dosage forms (tablets, gels, ointments, creams).

All of the suppositories listed have the same contraindication - individual hypersensitivity to some components of the suppository.

Single-component preparations (contain one antifungal substance):

Combination drugs (effective in treating other sexually transmitted infections):


To achieve the maximum effect from therapeutic actions, treatment should be carried out simultaneously to both sexual partners. Due to the lack of such actions, candidiasis can constantly recur due to the transition to a chronic form.

Antifungal rectal suppositories

Some medicinal suppositories can be produced not only for vaginal use, but also for rectal treatment of candidiasis in women. One of the advantages of some types of drugs is the possibility of use during the menstrual period and pregnancy. The most effective and inexpensive antifungal forms:

When treating candidiasis with antifungal suppositories, it is necessary to adhere to the prescribed treatment regimen to achieve maximum results and prevent the development of complications.

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The main advantages of this dosage form are a pronounced therapeutic effect and good interaction with the vaginal mucosa without causing side effects.

All suppositories and tablets can be used only after taking a smear on the vaginal flora and prescribing treatment for a fungal infection by a doctor. It is possible to achieve complete relief from thrush only through complex therapy of pathogenic microorganisms and the cause that provoked the development of candidiasis.

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Have you ever tried to get rid of THRUST? Judging by the fact that you are reading this article, victory was not on your side. And of course you know firsthand what it is:

  • white cheesy discharge from the external genitalia...
  • itching and burning in the vaginal area...
  • sour smell...
  • pain and discomfort when urinating, during sexual intercourse...

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Infection of a woman's genital organs with fungus is called candidiasis or thrush. The main method of treatment is the use of antifungal suppositories. The action develops as quickly as possible, while contact with the pathogen is made. Vaginal suppositories have been used in gynecology for a long time. Doctors bring this method to the fore before tablets.

For pregnant women, yeast in the intimate area should be treated only after consultation with a leading gynecologist

Antifungal suppositories in gynecology

Doctors advise using antifungal suppositories not only for severe symptoms, but also for carriers of the pathogen without symptoms. It is also necessary to undergo a course of treatment before operations and after long-term use of antibiotics. The chronic course of candidiasis requires various. Fungus control is effective when the type of fungus is known.

Vaginal and rectal suppositories are the main treatment for yeast infections. Benefits of therapy:

  • local effect on the fungus;
  • absence side effects;
  • speed of action - the woman feels the result within the next day.

The list of drugs is wide, but each of them often contains 2 components:

  • 1st destroys the yeast agent;
  • 2nd restores vaginal microflora.

There are several types of yeast, so you need to use different antifungal suppositories. There are cases when successful treatment of fungal diseases in gynecology ends with the restoration of symptoms after a few months. This means that the process has become chronic. Then suppositories and tablets are used against the fungus.

Features of application

Suppositories should be administered in a supine position.

Vaginal suppositories need to be inserted as deeply as possible so that maximum dissolution of the drug occurs at the site of contact. They must be used before bedtime, and in the morning after using the suppository, you need to stay in a horizontal position for at least 20 minutes for the suppository to spread normally throughout the vagina. Often 1 or 2 suppositories per day are required. The names of commonly used drugs that are suitable individually will be selected by the doctor.

List of drugs against fungus

Antifungal suppositories "Clotrimazole" for the intimate area

Suppositories for fungus, which are used in women with thrush, as well as for amoebic and trichomonas infections. The action is based on a direct effect on the shell of the pathological pathogen, producing a destructive effect. In addition to candles, a creamy form is offered. Pregnancy is a contraindication to the use of this remedy.

"Hexicon"


An effective remedy against thrush, can be used during pregnancy.

This is a drug whose main effect is antiseptic. It contains both an antibiotic and an antiseptic. Vaginal suppositories are used for 10 days. Exceptions are days with menstruation. The medicine is approved for use during pregnancy and breastfeeding.

"Polygynax"

A powerful drug for use in fungal diseases “for women”. The composition includes 2 antibacterial substances and 1 antiseptic, as well as a gel component, which is used to envelop the vaginal cavity. The course of treatment is 2 weeks. It can also be used for other genital infections, as well as to prevent the development of thrush.

"Pimafucin"

An antifungal agent that is very often used by women. The course of treatment with these suppositories is 3 days. In addition to vaginal suppositories, there are other forms of release - tablets and cream. The antibiotic that is part of this drug has a wide spectrum and is capable of destroying almost all types of fungus.

Suppositories are the most effective form for local treatment of thrush in women; some can relieve unpleasant symptoms the very next day after use. However, there are also disadvantages - it is impossible to cure thrush with vaginal suppositories alone; you need a complex with tableted antifungal drugs, otherwise the disease quickly becomes chronic.

In addition to vaginal suppositories, there are rectal suppositories that are prescribed to men and women:

  1. In the treatment of dysbiosis and intestinal candidiasis.
  2. For the prevention or treatment of urogenital thrush.

Rectal suppositories contain the same active antifungal substances as vaginal suppositories, the differences are size and shape (slightly smaller), and the presence of a small amount of anesthetic substances (for more comfortable administration). Prescriptions for the treatment of candidiasis in women are made by a gynecologist.

Thrush - what is it?

Thrush is caused by fungi such as Candida, which is why in medicine the disease is called candidiasis. Gynecologists say that to cure the disease it is better to use vaginal suppositories. Agents that act locally are characterized by fewer side effects, since the active substances are not absorbed into the blood, but kill pathogenic bacteria on the affected mucous membrane, and the inflammatory process is stopped and other symptoms of thrush are eliminated.

Factors affecting the development of candidiasis in females are as follows:

  1. Stressful condition, nervous breakdown;
  2. Decreased immunity;
  3. Eating low quality foods;
  4. Treatment with antibiotics;
  5. Carrying a child;
  6. Hormonal imbalance;
  7. Chronic diseases.

Thrush in women is manifested by the following symptoms:

  • profuse curdled or white vaginal discharge that has a sour odor;
  • the presence of burning, itching in the perineum;
  • pain when urinating, during sex;
  • redness and swelling of the mucous membranes;
  • discomfort in the lower abdomen, which may intensify after thermal procedures.

When female representatives are diagnosed with candidiasis, they use different methods, For example:

  1. Dietary nutrition is prescribed;
  2. Medications are used;
  3. Alternative medicine is used.

Treatment of candidiasis with medications is widespread. Thanks to them, it is possible to quickly and reliably get rid of the symptoms of the disease, as well as return the microflora in the reproductive organs to normal.

Similar medications are suppositories, creams and tablets. Thanks to the use of specialized medications, it is possible to cure candidiasis in both the initial and chronic forms.

How to use candles correctly?

Rules for using suppositories for thrush:

  1. Initially, you should study the description of the use of the medication in the instructions for use, since many drugs are moistened with boiled water before the process.
  2. It is better to place a suppository in the vagina at night; before the procedure, you should wash yourself thoroughly.
  3. Suppositories should be administered with pre-washed hands with trimmed nails or using fingertips.
  4. You need to insert the drug in a lying position, pushing it as deep as possible into the vagina, after which it is not advisable to get up for 30 minutes, giving time for the medication to dissolve. It is recommended to use daily sterile pads during the treatment of thrush.
  5. Treatment with vaginal suppositories is incompatible with sex and alcohol. Moreover, both partners must be treated (for men, rectal medications are purchased), regardless of the absence of signs of infection in the partner.

The use of suppositories will eliminate the source of inflammation at the first, simple stage of candidiasis. In case of advanced disease, suppositories for thrush in women can also be used, but as one of the components of complex therapy. The range of medications in the form of suppositories is huge, so we will look at suppositories for thrush in the table, where the list of names will go down from the best drugs to the less effective.

A short list of the best suppositories for the treatment of thrush

The best suppositories for thrush: price - quality:

  1. Zalain - the best effectiveness.
  2. Betadine is the leader of user voting (see).
  3. Macmiror complex - wide spectrum of action.

The best suppositories for thrush during pregnancy:

  1. Pimafucin is the most effective during pregnancy (see).
  2. Terzhinan - quick release from symptoms of thrush.
  3. Livarol - improved safety for mother and child.

The best inexpensive candles for thrush:

  1. Clotrimazole - best price.
  2. Nystatin is an inexpensive and effective drug (see).
  3. Hexicon has a pronounced antiseptic effect.

This category presents suppositories for thrush, which, according to user voting and expert opinion, have proven to be the most effective. Their high cost is more than compensated by the rapid relief of symptoms and long-lasting results. Positive reviews of these products confirm their pronounced antifungal effect.

The best suppositories for thrush: 2019 list

It is best to use inexpensive and effective suppositories to treat thrush - they act locally on the vaginal mucosa affected by the fungus and give best result than tablets, sprays.

To make it more convenient for you to choose the optimal remedy, we have compiled a list of the TOP 10 antifungal drugs in the form of vaginal suppositories.

The list is current for 2019:

Sertaconazole - Zalain

Zalain(price 1 soup. 480-520 rub.)

It is a derivative of benzothiophene and imidazole.

Use during pregnancy: There is no sufficient data on the potential harm to the fetus during breastfeeding. But given the one-time method of use and the lack of systemic action of Zalain - during pregnancy, lactation, it is possible to use it in a situation where the expected benefit for the woman is higher than the possible risk for the child.

Contraindications: Hypersensitivity

Side effects: itching in the vagina, burning sensation that does not require discontinuation of the drug, allergic reactions.

Mode of application: 1 suppository for thrush is inserted into the vagina at night once; if symptoms persist, re-use is possible after a week. Before use, wash the external genitalia with neutral soap. Can be used during menstruation.

Advantages and disadvantages: The advantage of using Zalain for thrush is the one-time administration of the drug, high efficiency, the ability to use during menstruation, the disadvantage is the high price.

Ketoconazole - Livarol

  • Livarol (price 430 rubles for 5 pcs. 600-800 for 10 pcs.)
  • Ketoconazole 230-400 rub.

Contraindications: hypersensitivity, 1st trimester of pregnancy, in the 2nd-3rd trimester with caution.

Side effects: irritation, redness of the vaginal mucosa, itching. Skin rash, urticaria.

Application: In a lying position, 1 suppository is inserted deeply into the vagina for 3-5 days, for chronic thrush for 10 days.

Pros and cons: The advantage is the rapid effect, virtually no allergic reactions. It is most often prescribed when a diagnosis is first established; with frequent or prolonged use, drug resistance occurs in the pathogen.

Itraconazole - Irunin

Irunin - vaginal tablets 10 pcs. 300-320 rub.

Contraindications: 1st trimester of pregnancy, in the 2nd-3rd trimester with caution, hypersensitivity, lactation period

Side effects: itching, burning, skin rash that does not require discontinuation of the drug.

Application: at night for 7-14 days.

Pros and cons: An effective remedy for recurrent thrush and resistance to other antifungal agents, the disadvantage is that it cannot be used in the 1st trimester.

Nystatin + Nifuratel

McMiror complex(price 680 rubles for 8 pcs.)

Pregnancy: approved for use

Contraindications: hypersensitivity

Side effects: very rarely itching, skin rash

Application: Intravaginally, 1 suppository 8 days before bedtime.

Advantages and disadvantages: The main advantage of the possibility of therapy during pregnancy, the disadvantage is the high price.

Clotrimazole

  • Clotrimazole(30-60 rubles 6 pieces),
  • Candide B6 (70 r), Antifungol, Kanesten,
  • Candizol, Yenamazole 100, Candibene.

Contraindications: increased sensitivity, it is strictly forbidden to use in the 1st trimester of pregnancy, while breastfeeding

Side effects: burning, itching, vaginal discharge, abdominal pain, headache, cystitis, frequent urination, pain during intercourse.

Mode of application: for 6 days, 1 suppository deep into the vagina at night.

Advantages and disadvantages: The advantage is that these are inexpensive suppositories against thrush, the disadvantage is frequent side effects, the rapid development of resistance in fungal agents.

Miconazole - Klion D, Neo-Penotran

Ginezol 7 (280-300 rubles), Gyno-dactanol, Daktarin, Mycozon (cream).
Combination drugs that contain, in addition to miconazole, metronidazole.

  • Klion-D 100 (price 330 rub.),
  • Neo-Penotran (14 pcs. 700 rub.),
  • Metromicon-Neo (14 pcs. 300-350 rub.)

Contraindications: hypersensitivity, with caution during pregnancy 2-3 trimester, lactation (suspend feeding during treatment) if diabetes mellitus, liver dysfunction, herpes

Side effects: Only at the beginning of treatment there may be a feeling of discomfort, burning, itching, nausea, diarrhea, abdominal pain.

Mode of application: for 6-7 days, 1 suppository at night, you cannot drink alcohol during treatment.

Pros and cons: quick effect, wide spectrum of activity, does not cause dysbacteriosis, effective for frequent relapses of thrush, the disadvantage is the danger of use during pregnancy and feeding a child.

Econazole

Gyno-pevaril(3 pcs. 420 rub. 15 pcs. 800 rub.), Ifenek

Contraindications: hypersensitivity, pregnancy (1 tr.), since it penetrates into the systemic bloodstream, in 2-3 with caution, breastfeeding should be stopped during feeding.

Side effects: local irritation, rash, itching.

Application: suppositories 50 mg. within 14 days, even after the symptoms disappear, the course must be completed. Suppositories 150 mg. - within 3 days, if after 7 days the culture test gives a positive result, the course of treatment should be repeated.

Advantages and disadvantages: effective suppositories for thrush.

Natamycin - Pimafucin

  • Primafungin (3 pcs. 220 RUR),
  • Pimafucin (price 3 pcs. 280 rubles. 6 pcs. 500-540 rubles)
  • Ecofucin 350 rub.

Effect on the fetus: approved for use during pregnancy

Contraindications: increased individual sensitivity

Side effects: slight irritation

Mode of application: for 3-6 days, 1 suppository.

Advantages and disadvantages: The advantage of Pimafucin for thrush is that it has no effect on the fetus, which is why it is prescribed during pregnancy.

Nystatin

Nystatin(30-60 rubles)
Complex preparations containing nystatin:

  • Polygynax (nystatin, neomycin, polymyxin B, price 6 pcs. 350 rub., 12 pcs. 600 rub.),
  • Terzhinan (prednisolone, neomycin, ternidazole, nystatin - 6 pcs. 360 rubles, 10 pcs. 450 rubles), but their use is fraught with the development of dysbacteriosis.

Contraindications: pregnancy of any stage, individual sensitivity

Side effects: chills, diarrhea, abdominal pain, vomiting, nausea

Mode of application: 2 times a day (morning and evening) for 10-14 days.

Pros and cons: The disadvantage of nystatin suppositories against candidiasis is the long course, use 2 times a day, and the presence of serious side effects. The advantage is that they are cheap; candida does not become resistant to nystatin, so it is often prescribed for chronic, recurrent candidiasis.

Povidone Iodine - Iodoxide

Iodoxide(10 pcs. 300 rub.), Betadine(price 7 pcs. 400 rub., 14 pcs. 500 rub.)

Contraindications: thyrotoxicosis, thyroid adenoma, with caution in case of renal failure, in case of individual sensitivity, not recommended during pregnancy, contraindicated in the 1st trimester, in the 2-3rd trimester and during lactation - with caution.

Side effects: allergic manifestations, local hyperemia

Mode of application: For acute vaginitis, 2 times a day for a week, 1 suppository, for chronic vaginitis, 1 time a day for 2 weeks, regardless of the phase of the menstrual cycle.

Pros and cons: can be used during menstruation, used in complex treatment for bacterial vaginosis.

To choose effective inexpensive suppositories for thrush in women, it is necessary, first of all, to determine the sensitivity of the candida fungus by conducting a bacterial culture and determining the resistance and sensitivity of the pathogen to a specific drug. The fact is that with chronic candidiasis with frequent relapses, treatment of thrush in women may be ineffective, since fungal pathogens develop resistance to the active components of the drugs.

It should be borne in mind that uncontrolled use of anti-candidiasis drugs for women can provoke the development of chronic thrush, as well as disruption of the vaginal microflora. It is also unacceptable to practice douching on your own against fungus, since as a result of such actions the disease can progress further and the microflora can be significantly disrupted. Therefore, every woman who is interested in suppositories for thrush, which are inexpensive and effective, should definitely visit a doctor and undergo an examination. Only a specialist, taking into account the clinical picture and sensitivity of the pathogen, can prescribe the most effective suppositories for thrush or complex therapy.

It should be taken into account that even if the symptoms of the disease disappear, and the woman believes that she has managed to cure the disease, a person who has no fungus according to laboratory data over the next three months is considered clinically healthy.

Pharmacies also offer special tests to determine candidiasis. The price of a test for thrush is from 600 rubles.

How to cure thrush with Flucostat in 1 day

You can take this medication after it has been prescribed by your doctor. It is important to follow a strict treatment regimen, which is selected individually for each patient. To prevent side effects and overdose, follow your doctor's instructions.

Flucostat (see) is produced in the form of capsules with a dosage of 50 or 150 grams of the active substance. The package contains one capsule.

  1. A mild form of thrush can be treated in 1 day with a 150 mg capsule- a single dose is sufficient.
  2. If the form of the pathology is severe, you need to take two capsules, namely 300 grams. The dosage is divided into two doses, seventy-two hours must pass between them.
  3. Recurrent, chronic form of candidiasis requires a longer course. For this, 3 doses of 150 grams are used, 72 hours apart.
  4. As a preventive measure, take 150 grams once a week for six months.
  5. The use of the drug can be combined with meals.
  6. Swallow the capsule whole, without chewing, with water.
  7. In some cases, combination therapy cannot be avoided.

Side effects are very rare. To avoid overdose, you must take Flucostat as prescribed by your doctor. The medication is not recommended to be taken during pregnancy, since the active component Fluconazole has a detrimental effect on the intrauterine development of the fetus.

A woman’s condition affects many organs. For example, thrush currently signals a decrease in immunity. This occurs due to many factors: from increased blood glucose to the development of gynecological pathologies. Thrush cannot be considered an infectious disease that can be transmitted to a partner.

It needs to be treated comprehensively, identifying the cause of its appearance, otherwise even the most effective suppositories for thrush can only help for a short time.

How to treat thrush?

You should not self-medicate and buy suppositories against thrush, which a friend or a salesperson at a pharmacy will recommend.

A gynecologist prescribes adequate treatment and not always from the first examination, but refers the patient for additional examination.

Often the problem appears against the background of other, more serious pathologies, such as diabetes mellitus, chronic inflammatory diseases ( HIV, tuberculosis), disorders in the digestive system and others.

Candidiasis colpitis– this is the medical name for thrush, it takes a long time to be treated, because the immune system affects the entire body. Especially with chronic pathologies, relapses cannot be avoided. Therefore, it is impossible to advise which suppositories are the most effective for thrush in women.

During treatment the following actions are carried out:

To treat thrush, suppositories from different pharmacological groups are used:

  • Antifungal agents.
  • Antibiotics that target Candida fungus.
  • Complex-action suppositories, which contain, in addition to antifungal substances, others.
  • Means that strengthen local immunity.

Precise List Definition effective drugs treatment will be carried out by a doctor after appropriate analysis and examination.

Treatment of thrush in women. Video:

Causes of thrush

For suppositories to help, you need to know the cause of thrush. Weakening of the immune system and the development of the disease occur under the influence of the following factors:

Infectious diseases.

Personal hygiene is of poor quality.

Hypothermia of the body.

The habit of using synthetic underwear.

Treatment with certain drugs, such as antibiotics.

Poor nutrition.

Changes in hormonal levels also occur during pregnancy.

Use of daily sanitary pads.

If the fungal infection is minor, then vaginal suppositories will help to cope with it. Your doctor will tell you which suppositories for thrush are best to use to eliminate the disease.

Cheap and effective suppositories for thrush

Every woman wants to find the most effective and safe candles, so that they quickly and efficiently help get rid of the problem, are safe and easy to use. All drugs can be divided into several groups.

Inexpensive but effective

Inexpensive and effective candles include the following:

1. Nystatin – average price 60-80 rubles for them. The fungus does not show resistance to the components of the drug, and therefore dies quickly. After treatment, a long-term effect is observed. Very convenient for chronic thrush.

It is used in advanced cases, but with long-term treatment, vaginal dysbiosis may occur, because the drug affects not only the pathogenic flora. Suppositories should be used 3 times a day.

Contraindicated for pregnant women and those who cannot tolerate the components of suppositories. Side effects rarely occur in the form of nausea, diarrhea and abdominal pain.

2. Clotrimazole - its price is 30-60 rubles. This drug has side effects such as abdominal pain, itching and discharge. Treatment with them lasts only 6 days, for which you should insert one suppository deep into the vagina at night. Contraindicated for pregnant women, especially in the early stages, and nursing mothers.

3. Synthomycin is an inexpensive suppository, 35-50 rubles. The active ingredient in them is macrolide antibiotics, which can disrupt metabolic processes in fungal membranes. These suppositories are used both during pregnancy and during breastfeeding. If used for a long time, microflora may be disrupted. It should be administered 2-3 times a day.

There are other drugs that can quickly get rid of the problem. But their use must be agreed with a doctor.

Expensive drugs

Effective and inexpensive suppositories for thrush have proven themselves positively, which is why they are still in demand among women. There are other drugs that are not so cheap, but at the same time preferable for use:

1. Pimafucin - 3 suppositories cost about 280 rubles. This drug is approved for pregnant women. Used in a course of 3-6 days, one per day. Not approved for use if hypersensitivity to the components is observed. A side effect is a slight burning sensation of the vaginal mucosa.

2. Lomexin - the price for a capsule of 10 g is 330 rubles, and for two capsules of 6 g - 450 rubles. A larger capsule is used once, and 6-gram capsules must be administered 2 days in a row. It's pretty effective remedy, quickly kills the fungus.

Contraindicated in case of hypersensitivity to the components and during pregnancy. Side effects include: rash, urticaria - in this case treatment must be discontinued, irritation - therapy can be continued.

3. Livarol - package price 450 rubles. In addition to getting rid of fungus, the drug helps cure some bacterial infections. Prescribed to those who have developed thrush for the first time. Cannot be used at the beginning of pregnancy, later only as prescribed by a doctor. Side effects are redness of the mucous membrane, itching and allergies in the form of rash and nausea.

4. Terzhinan - can be purchased at a price of 360-390 rubles. The drug is a complex action product. It contains neomycin, nystatin, ternidazole and prednisone. It can simultaneously treat other pathologies, for example, vaginitis.

Quickly relieves itching and inflammation. Side effects include individual intolerance and allergies. Cannot be used on early stages pregnancy. Treatment is prescribed by a doctor, but the drug cannot be used for more than two weeks.

5. Hexicon is an inexpensive drug, about 300 rubles per pack. The product is destructive to many types of pathogenic microflora. There are no contraindications for use; even pregnant women can be treated. Improper use can lead to vaginal dysbiosis. Suppositories must be administered deeply 1-2 times a day, the full course is prescribed by a doctor - this is 5 or 10 days.

6. Zalain - you can buy it for 500 rubles. The suppository is administered once and is a fairly effective drug. If symptoms have not disappeared, you can re-use after a week.

The suppository is inserted deep into the vagina at night. Side effects include itching, but there is no need to cancel treatment. Allergic reactions are possible. Do not use during pregnancy.

These are the most popular and best vaginal suppositories for thrush, but in fact there are many more of them, some expensive and some not so expensive. Only the doctor can decide which ones are right for you based on the results of the examination.

Proper treatment for thrush. Video:

Suppositories for milk production during pregnancy

Thrush is not as harmless as it seems. The advanced form spreads to the woman’s internal organs and can negatively affect reproductive function and make the woman infertile. When planning to conceive a child, it is necessary to cure thrush so that it does not interfere with pregnancy and does not harm the fetus during gestation.

In the later stages, it is also undesirable, since it can pass to the baby during childbirth. The best treatment at this time is local suppository therapy.

But not all of them can be used, otherwise particles of the drug, once in the blood, can harm the development of the baby.

You can be treated with safe and effective suppositories intended for use during pregnancy. The best suppositories for thrush during this period:

There is more useful information here.

  • Pimafucin;
  • Zalain;
  • Livarol;
  • Hexicon;
  • Clotrimazole.

These drugs have already been described above. You can also use other means:

The presented drugs have contraindications that should be taken into account before use. It is better to consult a doctor.

Suppositories for thrush during breastfeeding

After childbirth, when the mother breastfeeds the baby, the hormonal levels change and thrush almost always occurs. In order not to harm the baby’s health, treatment is carried out exclusively using suppositories. There are suppositories whose active substances penetrate into breast milk, so they cannot be used.

If you do not want to give up breastfeeding, you need to choose drugs that are safe for babies. These include: Clotrimazole, Hexicon, Zalain, Pimafucin. All of them are described above.

Suppositories for candidiasis and thrush are the most convenient in treating this disease. They are introduced deeply and are well absorbed by the vaginal mucosa, quickly relieving inflammation and killing harmful microorganisms. Don’t forget about the reasons for its appearance and use every opportunity to improve protective forces body.

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Suppositories for thrush are the most convenient way of local treatment of vaginal candidiasis in women. The effect of vaginal suppositories is due to the deep penetration of the active antifungal substance into the mucous membrane, which destroys the pathogen, eliminates inflammation, and reduces inflammation.

The pharmaceutical industry offers a wide range of different ones - these are both suppositories for local treatment and medications for oral administration, which are prescribed by a doctor for severe forms of candidiasis, for chronic thrush as part of complex therapy.

Which suppositories are best for thrush? There is one answer to this question - these are those drugs to which the candida fungus is sensitive based on the result of bacterial culture and determination of the resistance, resistance or sensitivity of the pathogen to a specific drug. Because in chronic, often recurrent cases, it may not be effective due to the development of drug resistance in fungal agents.

Uncontrolled, independent treatment of thrush leads to both the development of chronic candidiasis and disruption of the vaginal microflora. Moreover, many women actively practice this, which is not acceptable, since it only provokes further progression of the disease, further disrupting the vaginal microflora. Only the attending physician, based on the patient’s medical history, clinical picture, and taking into account the sensitivity of the pathogen, prescribes an adequate treatment regimen. Even if symptoms disappear, clinical recovery is considered to be the absence of fungi according to laboratory data over the next 3 months.

Rules for using suppositories against thrush

In the absence of therapy with a regular partner, a ping-pong effect occurs when a woman, after treatment, is again subjected to a fungal attack during unprotected sexual intercourse.

During therapy, you should either abstain from sexual intercourse or use condoms. Suppositories are inserted deep into the vagina at night to improve absorption of the drug.

When a woman is diagnosed with vaginal candidiasis, she and her doctor should analyze it, since without eliminating or minimizing the provoking factors, thrush can occur again and again.

Very often, candidiasis indicates the presence of other sexually transmitted infections (mycoplasmosis, gonorrhea, trichomoniasis, etc.) as well as the development of gardnerellosis ().

Depending on the intensity of symptoms, acute or chronic process, treatment may differ in the course of therapy, in some cases it is enough to use 1 suppository, but in a chronic process this is not enough and longer treatment is required.

  • Vaginal suppositories should not be used during menstruation, with the exception of Povidone-Iodine (Iodoxide, Betadine) and Sertaconazole (Zalain).
  • The following suppositories can be used for 1 suppository: Zalain, Lomexin
  • 3 suppositories each - Livarol, Gino-pevaril, Pimafucin.
  • 5-14 suppositories each - Macmiror, Clotrimazole, Ginesol, Iodoxide, Nystatin, Polygynax, Terzhinan, Irunin.

During treatment, you should not wear synthetic, tight-fitting underwear, you must follow all the rules of intimate hygiene, change towels and linen daily, do not use chemically scented pads, toilet paper, liquids for intimate hygiene, which only worsen the condition.

The best suppositories for thrush - Livarol, Pimafucin, Zalain, Nystatin, Clotrimazole, Lomixin, Macmiror - pros and cons of use

Sertaconazole - Zalain

Zalain(price 1 soup. 480-520 rubles, prices 2018)

It is a derivative of benzothiophene and imidazole.

Use during pregnancy: There is no sufficient data on the potential harm to the fetus during breastfeeding. But given the one-time method of use and the lack of systemic action of Zalain - during pregnancy, lactation, it is possible to use it in a situation where the expected benefit for the woman is higher than the possible risk for the child.
Contraindications: Hypersensitivity
Side effects: allergic reactions that do not require discontinuation of the drug.
Mode of application: 1 suppository for thrush is inserted into the vagina at night once; if symptoms persist, re-use is possible after a week. Before use, wash the external genitalia with neutral soap. Can be used during menstruation.
Advantages and disadvantages: The advantage of using Zalain for thrush is the one-time administration of the drug, high efficiency, the ability to use during menstruation, the disadvantage is the high price.

Ketoconazole - Livarol

  • Livarol (price 430 rubles for 5 pcs. 600-800 for 10 pcs.)
  • Ketoconazole 230-400 rub.

Contraindications: hypersensitivity, 1st trimester of pregnancy, in the 2nd-3rd trimester with caution.
Side effects: irritation, redness of the vaginal mucosa, itching. Skin rash, urticaria.
Application: In a lying position, 1 suppository is inserted deeply into the vagina for 3-5 days, for chronic thrush for 10 days.
Pros and cons: The advantage is the rapid effect, virtually no allergic reactions. It is most often prescribed when a diagnosis is first established; with frequent or prolonged use, drug resistance occurs in the pathogen.

Itraconazole - Irunin

Irunin - vaginal tablets 10 pcs. 300-320 rub.

Contraindications: 1st trimester of pregnancy, in the 2nd-3rd trimester with caution, hypersensitivity, lactation period
Side effects: itching, burning, skin rash that does not require discontinuation of the drug.
Application: at night for 7-14 days.
Pros and cons: An effective remedy for recurrent thrush and resistance to other antifungal agents, the disadvantage is that it cannot be used in the 1st trimester.

Nystatin + Nifuratel

(price 680 rubles for 8 pcs.)

Pregnancy: approved for use
Contraindications: hypersensitivity
Side effects: very rarely itching, skin rash
Application: Intravaginally, 1 suppository 8 days before bedtime.
Advantages and disadvantages: The main advantage of the possibility of therapy during pregnancy, the disadvantage is the high price.


  • (30-60 rubles 6 pieces),
  • Candide B6 (70 r), Antifungol, Kanesten,
  • Candizol, Yenamazole 100, Candibene.

Contraindications: increased sensitivity, it is strictly forbidden to use in the 1st trimester of pregnancy, while breastfeeding
Side effects: burning, itching, vaginal discharge, abdominal pain, headache, cystitis, frequent urination, pain during intercourse.
Mode of application: for 6 days, 1 suppository deep into the vagina at night.
Advantages and disadvantages: The advantage is that these are inexpensive suppositories against thrush, the disadvantage is frequent side effects, the rapid development of resistance in fungal agents.

Miconazole - Klion D, Neo-Penotran

Ginezol 7 (280-300 rubles), Gyno-dactanol, Daktarin, Mycozon (cream).
Combination drugs that contain, in addition to miconazole, metronidazole.

  • Klion-D 100 (price 330 rub.),
  • Neo-Penotran (14 pcs. 700 rub.),
  • Metromicon-Neo (14 pcs. 300-350 rub.)

Contraindications: hypersensitivity, with caution during pregnancy 2-3 trimester, lactation (suspend feeding during treatment) for diabetes mellitus, impaired liver function, herpes
Side effects: Only at the beginning of treatment there may be a feeling of discomfort, burning, itching, nausea, diarrhea, abdominal pain.
Mode of application: for 6-7 days, 1 suppository at night, you cannot drink alcohol during treatment.
Pros and cons: quick effect, wide spectrum of activity, does not cause dysbacteriosis, effective for frequent relapses of thrush, the disadvantage is the danger of use during pregnancy and feeding a child.

Econazole

Gyno-pevaril(3 pcs. 420 rub. 15 pcs. 800 rub.), Ifenek

Contraindications: hypersensitivity, pregnancy (1 tr.), since it penetrates into the systemic bloodstream, in 2-3 with caution, breastfeeding should be stopped during feeding.
Side effects: local irritation, rash, itching.
Application: suppositories 50 mg. within 14 days, even after the symptoms disappear, the course must be completed. Suppositories 150 mg. - within 3 days, if after 7 days the culture test gives a positive result, the course of treatment should be repeated.
Advantages and disadvantages: effective suppositories for thrush.

Natamycin - Pimafucin

Effect on the fetus: approved for use during pregnancy
Contraindications: increased individual sensitivity
Side effects: slight irritation
Mode of application: for 3-6 days, 1 suppository.
Advantages and disadvantages: The advantage of Pimafucin for thrush is that it has no effect on the fetus, which is why it is prescribed during pregnancy.

(30-60 rubles)
Complex preparations containing nystatin:

  • Polygynax (nystatin, neomycin, polymyxin B, price 6 pcs. 350 rub., 12 pcs. 600 rub.),
  • Terzhinan (prednisolone, neomycin, ternidazole, nystatin - 6 pcs. 360 rubles, 10 pcs. 450 rubles), but their use is fraught with the development of dysbacteriosis.

Contraindications: pregnancy of any stage, individual sensitivity
Side effects: chills, diarrhea, abdominal pain, vomiting, nausea
Mode of application: 2 times a day (morning and evening) for 10-14 days.
Pros and cons: The disadvantage of nystatin suppositories against candidiasis is the long course, use 2 times a day, and the presence of serious side effects. The advantage is that they are cheap; candida does not become resistant to nystatin, so it is often prescribed for chronic, recurrent candidiasis.

Povidone-iodine - Iodoxide

(10 pcs. 300 rub.), Betadine(price 7 pcs. 400 rub., 14 pcs. 500 rub.)

Contraindications: thyrotoxicosis, thyroid adenoma, with caution in case of renal failure, in case of individual sensitivity, not recommended during pregnancy, contraindicated in the 1st trimester, in the 2-3rd trimester and during lactation - with caution.
Side effects: allergic manifestations, local hyperemia
Mode of application: For acute vaginitis, 2 times a day for a week, 1 suppository, for chronic vaginitis, 1 time a day for 2 weeks, regardless of the phase of the menstrual cycle.
Pros and cons: can be used during menstruation, used in complex treatment for bacterial vaginosis.

Fenticonazole - Lomexin

(fenticonazole, price 1000 mg. 1 piece 400 rub. 600 mg. 2 pieces 600 rub.)

Contraindications: pregnancy, cannot be used during menstruation, if you are hypersensitive to the components of the suppository.
Side effects: mild symptoms of irritation that go away on their own and do not require discontinuation of the drug, allergic reactions - rash, urticaria, erythema
Mode of application: capsule 600 mg. are administered once; according to indications, if symptoms persist, use may be continued for 3 days. Capsules 1000 mg. administered within 2 days.
Advantages and disadvantages: effective remedy, cannot be used during pregnancy.

Dequalinium chloride - Fluomizin

Fluomizin - vaginal tablets 6 pcs. 560 rub. - antiseptic in gynecology (bacterial vaginosis, candidal vaginitis, sanitation before childbirth and operations)

Contraindications: ulcerative lesions of the cervix and vagina, girls before sexual activity, pregnancy 1-2 trimester - no data on the safety of use
Side effects: symptoms of irritation, allergic reactions - rash, urticaria, erythema
Mode of application: capsule at night for 6 days, stop treatment during menstruation and continue after.

In addition to suppositories, it is possible to use creams with antifungal drugs:

  • Clotrimazole - Candide (with applicator 80 rubles), Clotrimazole cream 120 rubles, Kanizon 80 rubles.
  • Econazole – Ecodax cream 140 RUR
  • Isoconazole - Travogen cream 500-700 rub.
  • Fenticonazole - Lomexin cream 600 rub.
  • Butoconazole - Gynofort cream with applicator 600-700 rub.

For chronic recurrent thrush, it is necessary to take antifungal drugs orally:

  • Fluconazole 40-50 rubles (and more expensive analogues Flucostat, Mikomax, Mikosist, Diflucan)
  • Tinidazole 30-70 rub.
  • Ketoconazole – Mycozoral 460 RUR
  • Itraconazole - Irunin 320 rubles, Itrazol 380 rubles, Orungamin.

After antifungal therapy, the doctor may prescribe medications to normalize the vaginal microflora, that is, create conditions for the growth of lactobacilli in the vagina:

  • Vagilak 2 times a day (suppositories with bifidobacteria) for 5-10 days.
  • Laktozhinal, Acylact (lactobacteria) vaginal capsules for 1-10 days.
  • For oral administration - Bificol 10 days.

Advantages and disadvantages of using suppositories for thrush

Advantages of using topical medications for candidiasis in women:

  • When the drug is administered to a place where fungi actively multiply, the effect of local treatment appears much faster, especially when using modern effective drugs such as Livarol or Zalain.
  • Modern antifungal agents can be used once.
  • Because systemic absorption of topical medications is low, the incidence of side effects is reduced, unlike oral therapy.

Disadvantages of local treatment:

  • Local treatment causes some inconvenience to a woman - it stains her underwear and limits her sex life.
  • A positive effect from such therapy is possible only in mild forms of thrush, but when the course of the disease is more severe and prolonged, local therapy should be supplemented with the use of. Therefore, it is often necessary to repeat the course of treatment after a certain time.
  • When using combined antimicrobial drugs, such as Terzhinan, Polygynax, a common side effect is vaginal dysbiosis, which then requires additional treatment, for example, the use of suppositories with lactobacilli - Lactonorma, Acylact, Lactobacterin, Ecofemin or Vagiflora.

Suppositories for thrush during pregnancy

Very often, thrush occurs in women during pregnancy due to a physiological decrease in immunity, and many drugs either categorically cannot be used, or reliable studies of safety for the fetus have not been carried out. Among the entire selection of local drugs, the following suppositories are approved for use:

  • Suppositories - Pimafucin, Primafungin (active ingredient Natamycin).
  • Combined drug - Macmiror complex (active ingredients Nystatin and Nifuratel).
  • In the 2-3 trimesters Clotrimazole, Nystatin (low effectiveness) or the ancient remedy Borax in glycerin (Sodium tetraborate in glycerin), Pimafucin, Gino-Pevaril, Ginofort (vaginal cream), all these drugs are used during pregnancy with caution if there is a potential risk for the health of the mother exceeds the risk for the child.

  • Some doctors prescribe a combination drug - Terzhinan (prednisolone, neomycin, ternidazole, nystatin), but the instructions for it indicate that from the 2nd trimester it can only be used when assessing the potential benefit to the mother and harm to the fetus, since it has undesirable side effects and contains a hormonal drug - prednisolone.